We help deliver impactful Science
Genomics
Analysis and functional annotation of next-generation DNA-sequencing data to delineate germline and somatic mutations
Targeted (Panel) Sequencing
Whole-exome sequencing
Whole-genome sequencing
Single-cell genomics
Transcriptomics
Expression quantification, differential expression analysis, and pathway enrichment analysis of next-generation RNA-sequencing data to identify differentially expressed genes and isoforms
Gene expression analysis
(Illumina short-read)
Alternative splicing analysis
(Illumina short-read)
Isoform expression analysis
(Nanopore long-read)
Isoform expression analysis
(PacBio long-read)
Single-cell transcriptomics
(Droplet-based: 10x Genomics)
Single-cell transcriptomics
(Plate-based: Smart-seq)
Microarray
Epi-genomics
Detection of regulatory elements ("peaks") and differtential peak analysis to infer chromatin state, identify transcription factor and protein binding sites, and DNA methylation markers
ChIP-sequencing
(Antibody-capture)
ATAC-sequencing
(Chromatin state)
Singcle-cell ATAC-sequencing
(10x Genomics)
Population Genetics
Genetic association analysis to identify novel risk loci and variants associated with disease or phenotype
Common variant association analysis (GWAS)
Rare variant association analysis (ExWAS)
Gene-level association analysis
Polygenic risk scoring
Mendelian randomisation
Meta-analysis
Survival analysis
Viral Genetics
Genetics analysis of viral DNA/RNA sequences for infectious disease surveillance
de novo assembly
Phylogenetic analysis
Amino acid polymorphism analysis
